NexGard
NexGard contains afoxolaner, a novel member of the isoxazoline chemical class. Afoxolaner kills fleas and ticks by targeting a distinct binding site within nerve cell membrane GABA (gamma aminobutyric-acid) – modulated chloride channels, resulting in uncontrolled hyperexcitation and death.
Dosage:
NexGard is a once a month oral palatable braised beef flavoured soft chew with a recommended minimum dose level of 2.5mg/kg bodyweight, effective against fleas and ticks, and with published efficacy studies on generalised demodecosis, sarcoptic and otodectic mange.