Nefrotec is effective at preventing and dissolving stones and sediment in the bladder and kidneys.For both male cats and dogs, stones or ‘sand’ in the bladder can become critical, blocking the urethra and preventing urination. In this case, contact your Vet immediately and always ensure proper diagnosis and suitability.Directions for Use:To be given orally or mixed with food or as directed.DogsSmall breeds1 tablet twice dailyLarge breeds2 tablets twice dailyCats1 tablet twice daily